Disturbances of the Combustion Processes in Muscular Disorders.

Attempts to elucidate carbohydrate metabolism in muscular diseases have been made by a relatively large number of authors but the results obtained, often contradictory, seem to be difficult to classify in a cycle of metabolic disorders. Nevertheless disturbances of carbohydrate metabolism appear to play an important role in the pathogenesis of muscular diseases. In view of the key position of pyruvic acid in the metabolic processes, it seemed interesting to investigate further its metabolism, all the more so, as the literature suggests that the blood pyruvic acid level is raised in progressive muscular dystrophy.